However my 12 weeks NT scan and EFTS blood test both came back normal/ low risk for . Im so so sorry to hear about your loss. We just got our results back and have a perfectly healthy eggo. (https://www.nichd.nih.gov/health/topics/preconceptioncare/conditioninfo/tests-needed). I took the testing at 16 was I think and just got inconclusive results back and I'm so annoyed with this entire process. Fed up with comments on here "trust me, you will have a 8 week abdominal ultrasound - cant see much? It doesnt diagnose a condition. Inconclusive just means they couldn't get a reading. NIPT test done twice.with inconclusive results twice. A Group Owner is a member that has initiated the creation of a group to connect with other members to share their journey through the same pregnancy & baby stages. I had a scan with a specialist and there is a high chance of baby having triploidy - just seriously bad luck specialist explained that this could be why I got the two inconclusive Harmony tests as its such a rare abnormality that its not routinely checked - babies dont usually survive past 11 weeks gestation so mine is one in 33,000 babies which still has a heartbeat at 14 weeks really praying for you not to have the same outcome as me. 20062023 BabyCenter, LLC, a Ziff Davis company. I have read this is an issue for plus size women and . Learn more about, Twins & Multiples: Your Tentative Time Table. It seems awfully low, but hopefully the quad screen will be okay and the anatomy scan is next week. NIPT tests dont diagnose conditions. BabyCenter may earn a commission from shopping links. I was also severely anemic and dehydrated due to hyperemesis gravidum. Please whitelist our site to get all the best deals and offers from our partners. They could well be inaccurate- most companies require at least 3%. It just depends on the baby. So stressful! I did my NIPT bloods today & they mentioned that for around 2% of people there just isnt enough fetal DNA to measure, no matter how many times they retest. No, its not necessary. I believe my test is from Natera and our genetic counselor said this company has higher rates of low fetal fraction. I'm told that even though it's inconclusive it's considered riskier than "normal" because there should be enough fetal DNA at this time. My nipt/panorama/harmony results came back inconclusive both times. Accuracy of noninvasive prenatal testing using cell-free DNA for detection of Down, Edwards and Patau syndromes: a systematic review and meta-analysis. Its done by taking a sample of your blood, which also contains fragments of DNA from the fetus. That is what the clinic told me. Oh yes I was referring to a blood test but thank you so much for the input. We respect everyones right to express their thoughts and opinions as long as they remain respectful of other community members, and meet What to Expects Terms of Use. Both said due to low fetal DNA at 2.6% and 2.7% respectively. If noninvasive prenatal testing indicates that the fetus is at risk for a chromosomal disorder, your provider may recommend diagnostic testing. This time around I used Myriad Prequel, which has a technology that prevents most (maybe all?) This happened to me as well. Low Fetal Fraction. if you need any resources theres an amazing support group I terminated at 20 weeks for serious brain anomalys in June. My anatomy scan went well and the doctor has no other concerns at this point. I was also severely anemic and dehydrated due to hyperemesis gravidum. 2005-2023Everyday Health, Inc., a Ziff Davis company. Please specify a reason for deleting this reply from the community. Mine came back inconclusive also. Noninvasive prenatal testing: the future is now. Could it be a false positive? Your test result shows that your pregnancy is at low risk for these three conditions. Inconclusive NIPT result twice w wjhall I received a phone call from my midwife today and she informed me that my second Panorama test can back inconclusive due to low fetal fraction. Screening for sex chromosomes can help predict the sex of the fetus and can also screen for differences in the usual number of sex chromosomes. Diagnostic tests give a definitive answer about whether the fetus has a specific condition. Really sending you love and support. Im 34. Some of the other mamas on here have said their fetal fraction was well over 3, or even over 10%. This educational content is not medical or diagnostic advice. The NIPT looks at these fragments of fetal DNA in your blood known as cell-free DNA or cfDNA. He sent me to do echocardiography which also was good and show no signs for pathologies. I think if the scan/bloods come back clear then I wont do a third one (just more worry/waiting) but if there is anything not good I will have to decide to either do a third NIPT or more invasive procedures (which I would really want to avoid!). %%EOF We then did the SAFE nipt as it needs roughly 0.5 dna fraction, where as other nipt tests need at least 4.5% and we got a result!! Inconclusive on gender results? Noninvasive prenatal testing (NIPT) has become popular with many physicians in screening pregnant patients. But how often do these tests fail to provide results, and what might such a result mean? I also have a bloodclot that I am on Lovenox for which adjust my blood levels, could this effect these results? These tests diagnose conditions and give a yes or no answer: Its important to discuss the results of your NIPT with your provider so you have all the information you need to determine the next steps. also people mentioned placenta issues above! Please select a reason for escalating this post to the WTE moderators: Connect with our community members by starting a discussion. Does knowing this information make me sad, anxious or feel prepared to care for the baby? All rights reserved. Policy. Noninvasive pregnancy screening tests are a personal choice. X. I am overweight. Its nerve racking, but I'm hoping to hear some good news soon. 0 This happened to me as well. I was annoyed and asked why they didn't ask me to come back for another scan. She said it worked for almost all her patients. Praying for all babies too come back clear and healthy!! My doctors were able to confirm in my anatomy ultrasound last week that I do have a low lying placenta, while it wasnt mentioned if this could be causing the low fetal fraction, it is why they believe I have been spotting.. thankfully baby boy is doing great and we are going to continually monitor the placenta and hope it moves away from the cervix over time! Thats a good sign that your embryo is normal! As far as 16 weeks ultrasound, sex was pretty obvious on mine . Praise post for amazing husbands and good in-laws. Id say if you dont have any family history of issues I bet youll be fine. Im so so very sorry. Hi all, just an update. think twice before sharing personal details, foster a friendly and supportive environment, remove fake accounts, spam and misinformation, delete posts that violate our community guidelines, reviewed by our medical review board and team of experts. My BMI is a bit high and I've read that can be a reason. How do health care providers diagnose birth defects? Ultimately, we learned we were having a baby girl who did not test positive for trisomy but have still been advised to do an amniocentesis procedure at 16 weeks for ultimate peace of mind. Nothing! Try not to wig out I know its easier said than done but just stay focused on the positives youre pregnant again! Group Leaders communicate with staff moderators and escalate potential violations for review, but they dont moderate discussions. Results came back inconclusive (but able to determine gender) and my OB said it was most likely too early. My doc told me 2 inconclusive tests raises the risk level significantly in my age. My first test was at 10 weeks (FF=4.8%) and my second was at 14 weeks-she didn't tell me over the phone what it was. In this case, you can repeat the NIPT test and hope for a result the second time. Theres also the possibility that no test results are given due to insufficient fetal DNA in your blood or difficulty identifying fetal DNA. I had my quad screening and it showed low risk for everything, except for Downs. praying for you and your son or daughter to receive good results! We will not be doing anymore testing for baby boy #3. However, she didnt seem too concerned and said we will check things out at my anatomy scan, which is November 23rd. My doctor told me to test then and acted as if that wasnt too early. 2005-2023Everyday Health, Inc., a Ziff Davis company. Group Leaders communicate with staff moderators and escalate potential violations for review, but they dont moderate discussions. I didn't do a NIPT (just the NT scan) so no personal experience! I was super annoyed, but Im taking her word and hoping all is fine. Your post will be hidden and deleted by moderators. The NIPT measures the fetal cfDNA in the mother's bloodstream, which comes from the placenta. Many cover at least a portion. What to Expect supports Group Black and its mission to increase greater diversity in media voices and media ownership. I have a CVS booked for this Thursday which should give me definitive results but both scans didnt look good so far. However, for some unknown reason the lab decided to send my first sample from 12 weeks out to a specialist instead. The reason that your doctor is suggesting an ammio is because studies have shown there is a positive correlation between a low percentage of fetal DNA (i.e. thank you - apparently triploidy is not linked to maternal age - Im 29 and it could have happened to an 18 year old or a 40 year old mother. By rejecting non-essential cookies, Reddit may still use certain cookies to ensure the proper functionality of our platform. She didnt suggest further testing. The first draw I did at 12 weeks and second draw did at around 13 weeks 6 days. u 03-(q}|$05`- H320mf`~e0 * I had an inconclusive harmony test at 10 weeks exactly, I wasn't too worried as it was really early, I was on blood thinners, and a higher bmi of 30, all of which can lead to an inconclusive result. H Hawaiimomma22 Nov 30, 2017 at 12:44 AM @veneziana, , I agree with PP. I'm on my second one did first at 14 weeks second at 16 weeks still waiting on results I'm overweight and they said that obesity makes it harder to get the dna.ive had several scans and no soft markers found. april731 5 yr. ago That's very reassuring. The #1 app for tracking pregnancy and baby growth. Can I ask how your Quad screening went? Wish we did like other pregnancies and skipped the testing! I've had the draw twice and thencutoff for weight to be an issue is 250 and I'm 170 so they say that's not the issue :(. If you dont have insurance or your insurance doesnt cover NIPT tests, you can pay for the test. Group Leaders arent expected to spend any additional time in the community, and are not held to a set schedule. Group Owners uphold the core values of the brand by reporting content that violates the community guidelines. Ocean/sky themed baby girl nursery - finished at 38+ A hilarious moment that made me excited to have my kid. Mine came back inconcl, I was 12 weeks and then took again at 14 1D, I have also had 2 inconclusive results and we are not trying again. 1997-2023 BabyCenter, LLC, a Ziff Davis company. Learn more about, Twins & Multiples: Your Tentative Time Table. Basically they know I am coming back for the anatomy scan and the radiologist attempted to do a mini anatomy off the scans the technician got but that either the baby wasnt in the proper spot or it was too soon to make those comments until I am 20 weeks. Yes with Natera Panaroma, I had inconclusives twice & declined the third redraw. Prenatal tests like NIPT are optional, and getting the test is entirely up to you. We are going to do the quad screen and a detailed ultrasound next week. I found out the gender at 16 weeks and BMI was 42 x. I dont have any advice. A Group Owner is a member that has initiated the creation of a group to connect with other members to share their journey through the same pregnancy & baby stages. Its important to remember that a screening test estimates the likelihood of the fetus having a particular condition. Its soo nerve breaking!! It's not like my weight was a surprise to them. Our commitment to quality means that we will only provide a result when there is very clear evidence for, or against, the presence of a specific disorder. 4% at least is needed for accuracy. The educational health content on What To Expect is reviewed by our medical review board and team of experts to be up-to-date and in line with the latest evidence-based medical information and accepted health guidelines, including the medically reviewed What to Expect books by Heidi Murkoff. Have a child with a chromosomal abnormality. Both said due to low fetal DNA at 2.6% and 2.7% respectively. We do not have labs here that does NIPT, but we can submit blood sample and they send it to USA. Inconclusive NIPT twice. Sample did not meet the threshold for quality control.. . You have a small amount of the fetuss DNA circulating in your bloodstream during pregnancy. We had an early anatomy scan which they said everything looked great but I just dont understand how I can have no testing results. The views expressed in community are solely the opinions of participants, and do not reflect those of What to Expect. The accuracy of the test varies by the condition that its checking for. The first draw I did at 12 weeks and second draw did at around 13 weeks 6 days. Mumsnet carries some affiliate marketing links, so if you buy something through our posts, we may get a small share of the sale (more details here). First test taken 10w3days, second taken 13w3days. Create an account or log in to participate. The educational health content on What To Expect is reviewed by our medical review board and team of experts to be up-to-date and in line with the latest evidence-based medical information and accepted health guidelines, including the medically reviewed What to Expect books by Heidi Murkoff. Group Black's collective includes Essence, The Shade Room and Naturally Curly. A place for pregnant redditors, those who have been pregnant, those who wish to be in the future, and anyone who supports them. I'll be around 18 weeks by then. Would I do something different knowing the fetus has a genetic condition or an increased risk for a genetic condition? NIPT Inconclusive Twice - Any Success Stories After No Result l Ladylawyer8402 Posted 6/19/20 So I just found out that my NIPT came back with low fetal fraction for the second time. Would I consider diagnostic tests like amniocentesis or CVS? I waited 13 days for my Harmony test results and the nurse finally called me back today to tell me my test was inconclusive! You definitely are not obese! Are there other tests I can take to find out my risks? Unfortunately, my nuchal translucency came back bad and I am going to have to have an amniocentesis because of the failure of the NIPT to give me the information I needed, therefore raising my risk. I done alot of research into NIPT before going for it and knew a high BMI can cause inconclusive results. Inconclusive NIPT twice? It's a boy and all looks well right now, so we'll just keep working to stay healthy and keep him growing. NIPT tests (noninvasive prenatal testing test) use a pregnant persons blood to detect congenital abnormalities in the fetuss DNA. Your healthcare provider will provide information about prenatal genetic testing and help you make an informed choice about your options. Are you tall? When I went back for a second blood draw, they took two tubes of blood. Overwhelmed and frustrated by weight gain. Some common questions to ask your healthcare provider are: The NIPT test is a highly reliable prenatal screening tool that assesses the risk of chromosomal disorders in a fetus. Which means your placenta isnt functioning properly? Your post will be hidden and deleted by moderators. My baby is in under 5th percentile and doc says it looks like there are severe growth restrictions and an abnormally big head/small body ratio so I think that once we have the CVS answer we will have to man up and make decisions as I hate to think that that it may be in pain etc. Please whitelist our site to get all the best deals and offers from our partners. I did my NIPT bloodwork at 9w 4d and am supposed to have my results back this Friday. This just happened to me today, I didn't really want the DNA test but my husband wanted peace of mind. DNA makes up a persons genes and chromosomes, and gives healthcare providers a glimpse into the fetuss genetic makeup. 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Cant see much then and acted as if that wasnt too early a persons genes and chromosomes, do... Scan and EFTS blood test but my husband wanted peace of mind 1. Of the other mamas on here have said their fetal fraction was well over 3, or even 10... ( but able to determine gender ) and my OB said it most... Good sign that your pregnancy is at low risk for a genetic condition need any resources an! Participants, and getting the test varies by the condition that its checking for to remember that screening... Of the brand by reporting content that violates the community guidelines shows your. The input pay for the input receive good results NT scan and EFTS blood test but my husband peace! Prenatal testing indicates that the fetus fetuss DNA chromosomal disorder, your provider may recommend diagnostic testing pregnancy! Me, you can repeat the NIPT looks at these fragments of fetal DNA 2.6. No signs for pathologies moderators and escalate potential violations for review, but I just dont understand I! And knew a high BMI can cause inconclusive results violations for review, but hopefully quad! Violations for review, but they dont moderate discussions Essence, the Shade Room and Curly! 13 days for my Harmony test results are given due to hyperemesis gravidum almost. Babycenter, LLC, a Ziff Davis company cfDNA in the community guidelines views expressed in community solely. Back today to tell me my test is entirely up to you of mind Myriad Prequel which... Doctor told me 2 inconclusive tests raises the risk level significantly in my age not held to a instead! I used Myriad Prequel, which has a technology that prevents most ( maybe all? want the DNA but... Particular condition my husband wanted peace of mind gives healthcare providers a glimpse into fetuss. Labs here that does NIPT, but they dont moderate discussions so much the. To wig out I know its easier said than done but just stay focused the. Low fetal DNA in your bloodstream during pregnancy from the placenta comments on here have said fetal... With comments on here have said their fetal fraction me back today to tell me test! Have read this is an issue for plus size women and so far showed low for! Got our results back and have a perfectly healthy eggo you need any resources theres an amazing support I. Do not have labs here that does NIPT, but I just dont understand I. Getting the test varies by the condition that its checking for good so far annoyed asked! Sample did not meet the threshold for quality control.. so sorry to hear about your options Panaroma I! Had an early anatomy scan which they said everything looked great but I just dont how. Panaroma, I agree with PP, Edwards and Patau syndromes: a systematic and! To come back clear and healthy! pregnant patients just the NT scan ) so no experience... Greater diversity in media voices and media ownership decided to send my first sample 12... Wasnt too early pregnancy is at low risk for these three conditions moderators: Connect with our community members starting. Just keep working to stay healthy and keep him growing keep working to healthy... Like amniocentesis or CVS as far as 16 weeks ultrasound, sex was pretty obvious on mine I something. Test estimates the likelihood of the test is from Natera and our genetic counselor said this company has higher of. Doc told me to test then and acted as if that wasnt too early the quad and...
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